References
(1) RCSB Protein Data Bank. http://www.rcsb.org/pdb/home/home.do.
(2) Cheeseman, M. D. et al., 2016. Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70. Journal of Medicinal Chemistry 59: 4625−4636.
(3) Powers, M. V. et al., 2010. Targeting HSP70: The second potentially druggable heat shock protein and molecular chaperone? Cell Cycle 9: 1542-1550.
(4) Powers, M. V., Clarke P. A., Workman, P., 2008. Dual Targeting of HSC70 and HSP72 Inhibits HSP90 Function and Induces Tumor-Specific Apoptosis. Cancer Cell 14: 250–262.
(5) Brocchieri, L., Conway de Macario, E. and Macario, A., 2008. hsp70 genes in the human genome: Conservation and differentiation patterns predict a wide array of overlapping and specialized functions. BMC Evolutionary Biology 8: 19-39.
(6) Noonan, E. J. et al., 2007. Hsp70B regulation and function. Cell Stress & Chaperones 12: 219-229.
(7) Wisniewska, M. et al., 2010. Crystal Structures of the ATPase Domains of Four Human Hsp70 Isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B’, and HSPA5/BiP/GRP78. PloS ONE 5: e8625.
(8) Ricci, L. and Williams, K. P., 2008. Development of Fluorescence Polarization Assays for the Molecular Chaperone Hsp70 Family Members: Hsp72 and DnaK. Current Chemical Genomics 2: 90-95.
(9) Swain, J. F. et al., 2007. Hsp70 chaperone ligands control domain association via an allosteric mechanism mediated by the interdomain linker. Mol Cell 26: 27-39.
(10) Protein identification and analysis tools on the ExPASy server. Gasteiger, E. et. al. In J. M. Walker (Ed.) The proteomics protocols handbook. Totowa, New Jersey: Humana Press Inc. 2005.
(11) Dali server: conservation mapping in 3D. Nucl. Acids Res. 38, W545-549. Holm L, Rosenström, P. 2010.
(12) Basic Local Alignment Search Tool. National Center for Biotechnology Information. 2012. http://www.ncbi.nlm.nih.gov/blast/Blast.cgi
(13) Erbse, A., Mayer, M.P. and Bukau, B., 2004. Mechanism of substrate recognition by Hsp70 chaperones. Biochemical Society Transactions 32: 617-621.
(14) Hightower, L. E., Sadis, S. E., Takenaka, I. M., 1994. Interactions of Vertebrate hsc70 and hsp70 with Unfolded Proteins and Peptides. Cold Spring Harbor Monograph Archive 26: 179-207.
(15) Zhang, P. et al., 2014. Crystal Structure of the Stress-Inducible Human Heat Shock Protein 70 Substrate-Binding Domain in Complex with Peptide Substrate. PLoS One 9: e103518.